The query results for PTPN22 1858C/T , total 48 literatures
There are some abbreviations existing in the query results. For example, RA is an abbreviation for rheumatoid arthritis, H is an abbreviation for healthy controls...more

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Pubmed_ID Title Country Population

15208781
A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis.
 US American

15641066
Association of a functional single-nucleotide polymorphism of PTPN22, encoding lymphoid protein phosphatase, with rheumatoid arthritis and systemic lupus erythematosus.
 Spain European

15674368
The PTPN22 R620W polymorphism associates with RF positive rheumatoid arthritis in a dose-dependent manner but not with HLA-SE status.
 US American

15759012
Association analysis of the 1858C>T polymorphism in the PTPN22 gene in juvenile idiopathic arthritis and other autoimmune diseases.
 Norway European

15934099
Association between the PTPN22 gene and rheumatoid arthritis and juvenile idiopathic arthritis in a UK population: further support that PTPN22 is an autoimmunity gene.
 UK European

15986374
Association of the lymphoid tyrosine phosphatase R620W variant with rheumatoid arthritis, but not Crohn's disease, in Canadian populations.
 Canada American

16107870
Finnish case-control and family studies support PTPN22 R620W polymorphism as a risk factor in rheumatoid arthritis, but suggest only minimal or no effect in juvenile idiopathic arthritis.
 US American

16145680
Association of the PTPN22 C1858T single-nucleotide polymorphism with rheumatoid arthritis phenotypes in an inception cohort.
 Holland European

16163373
PTPN22 C1858T polymorphism in Colombian patients with autoimmune diseases.
 Colombia American

16175503
PTPN22 genetic variation: evidence for multiple variants associated with rheumatoid arthritis.
 US American

16277672
Rheumatoid arthritis seropositive for the rheumatoid factor is linked to the protein tyrosine phosphatase nonreceptor 22-620W allele.
 France European

16490755
Effects of PTPN22 C1858T polymorphism on susceptibility and clinical characteristics of British Caucasian rheumatoid arthritis patients.
 UK European

16635271
Association of PTPN22 1858 single-nucleotide polymorphism with rheumatoid arthritis in a German cohort: higher frequency of the risk allele in male compared to female patients.
 Germany European

16690758
Haplotype analysis revealed no association between the PTPN22 gene and RA in a Japanese population.
 Japan Asian

17135225
The 620W allele is the PTPN22 genetic variant conferring susceptibility to RA in a Dutch population.
 Holland European

17170052
Investigation of genetic variation across the protein tyrosine phosphatase gene in patients with rheumatoid arthritis in the UK.
 UK European

17553139
The PTPN22 1858C/T polymorphism is associated with anti-cyclic citrullinated peptide antibody-positive early rheumatoid arthritis in northern Sweden.
 Sweden European

17579671
Association of PTPN22 single nucleotide polymorphism with rheumatoid arthritis but not with allergic asthma.
 Poland European

17661906
The PTPN22 promoter polymorphism -1123G>C association cannot be distinguished from the 1858C>T association in a Norwegian rheumatoid arthritis material.
 Norway European

17696275
Association of PTPN22 with rheumatoid arthritis among South Asians in the UK.
 UK European

17804836
TRAF1-C5 as a risk locus for rheumatoid arthritis--a genomewide study.
 US,Sweden American,European

18474664
Testing for linkage and association with rheumatoid arthritis a ptpn22 promoter polymorphism reported to be associated and linked with type 1 diabetes in the Caucasian population.
 NA NA

18668548
Genome-wide association study of rheumatoid arthritis in the Spanish population: KLF12 as a risk locus for rheumatoid arthritis susceptibility.
 Spain European

19180477
Genetic risk factors for rheumatoid arthritis differ in Caucasian and Korean populations.
 Korea Asian

19343596
The R620W polymorphism of the protein tyrosine phosphatase 22 gene in autoimmune thyroid diseases and rheumatoid arthritis in the Tunisian population.
 Tunisia African

19357851
No association of PTPN22 gene polymorphism with rheumatoid arthritis in Turkey.
 Turkey Asian

19445664
Association of common polymorphisms in known susceptibility genes with rheumatoid arthritis in a Slovak population using osteoarthritis patients as controls.
 Slovakia European

19503088
REL, encoding a member of the NF-kappaB family of transcription factors, is a newly defined risk locus for rheumatoid arthritis.
 America American

19648290
Common and different genetic background for rheumatoid arthritis and coeliac disease.
 Holland European

20309874
Rheumatoid arthritis risk allele PTPRC is also associated with response to anti-tumor necrosis factor alpha therapy.
 US American

20707220
Functional polymorphisms of PTPN22 and FcgR genes in Tunisian patients with rheumatoid arthritis.
 Tunisia African

20822712
Lack of association of PTPN22, STAT4 and TRAF1/C5 gene polymorphisms with cardiovascular risk in rheumatoid arthritis.
 Spain European

20888443
PTPN22 1858C>T polymorphism is strongly associated with rheumatoid arthritis but not with a response to methotrexate therapy.
 Poland European

21120996
Most common single-nucleotide polymorphisms associated with rheumatoid arthritis in persons of European ancestry confer risk of rheumatoid arthritis in African Americans.
 US European

21279993
The PTPN22 R263Q polymorphism is a risk factor for rheumatoid arthritis in Caucasian case-control samples.
 Spain,NewZealand,UK,Norway,Holland,Germany European

21467606
Association of PTPN22 1858T/T genotype with type 1 diabetes, Graves' disease but not with rheumatoid arthritis in Russian population.
 Russia European

21506938
Association of the PTPN22 gene polymorphism with autoantibody positivity in Turkish rheumatoid arthritis patients.
 Turkey Asian

21614018
Non-HLA genes modulate the risk of rheumatoid arthritis associated with HLA-DRB1 in a susceptible North American Native population.
 Canada American

21949702
PTPN22 1858C>T polymorphism distribution in Europe and association with rheumatoid arthritis: case-control study and meta-analysis.
 Italy European

21965649
Evidence for PTPN22 R620W polymorphism as the sole common risk variant for rheumatoid arthritis in the 1p13.2 region.
 Spain,Holland,Norway European

22150086
Association of protein tyrosine phosphatase non-receptor 22 (PTPN22) rs2476601 and Kruppel-like factor 12 (KLF12) rs1324913 single nucleotide polymorphisms with rheumatoid arthritis in a Latvian population.
 Latvia European

22355377
Caucasian and Asian specific rheumatoid arthritis risk loci reveal limited replication and apparent allelic heterogeneity in north Indians.
 India American

22661644
Genetic markers of rheumatoid arthritis susceptibility in anti-citrullinated peptide antibody negative patients.
 UK Europeana(CaucAsian)

22704547
The PTPN22 C1858T variant as a risk factor for rheumatoid arthritis and systemic lupus erythematosus but not for systemic sclerosis in the Colombian population.
 Colombia American

22743847
The +1858C/T PTPN22 gene polymorphism confers genetic susceptibility to rheumatoid arthritis in Mexican population from the Western Mexico.
 WesternMexico American

23143596
High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis.
 Sweden,Holland,Spain,US,Canada,UK European

23350658
Association of PTPN22 rs2476601 and EGFR rs17337023 Gene polymorphisms and rheumatoid arthritis in Zahedan, Southeast Iran.
 Iran Asian

23378462
Replication of European rheumatoid arthritis loci in a Pakistani population.
 Pakistan Asian

Risk allele : People who carry this allele have a higher risk of developing rheumatoid arthritis than those without this allele.
Related allele in clinical features : Patients with rheumatoid arthritis who carry this allele have different clinical features (such as RF status, ACCP status, age of onset) compared to those without this allele.
Related allele in pharmacogenomics : Patients with rheumatoid arthritis carry this allele are less responsive to drug treatment than those without this allele.
Related allele in cardiovascular (CV) disease : RA patients with this allele have a higher risk of developing CV events than those without this allele.
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